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Table 1 miR-130b/301b expression in PrCa datasets

From: An integrated view of the role of miR-130b/301b miRNA cluster in prostate cancer

Repository Disease condition Sample type miR Deregulation Fold change p value PMID
GSE65061 Early/late recurrence FFPE tissue 301b UP4 1.7 0.026 25760964
GSE26245 Recurrent/non-recurrent FFPE tissue 130b UP4 1.2 0.024 21703393
GSE26247 Recurrent/non-recurrent FFPE tissue 130b UP4 1.3 0.017 21703393
Personal communication Metastatic/primary tumor Frozen tissue 130b UP4 1.6 NA 21765474
GSE35813 PC-3/RWPE-1 Cell lines 130b and 301b UP4 1.7 and 1.5 0.011 and 0.0091 22982408
GSE80400 Tumor/normal Frozen tissue 130b UP4 1.9 0.14 26041889
GSE21032, GSE21036, E-TABM-794 Tumor/normal
Recurrent/non-recurrent 		Frozen tissue 130b UP3 NA
NA 		NA
0.004 		26489476
GSE34933, GSE21032, GSE26367 Tumor/normal Frozen and FFPE tissue 130b UP3 NA 0.00000035 27179774
GSE21036 (PMID 20579941) Primary tumor/normal
Metastatic/primary tumor
Metastatic tumor/normal 		Frozen tissue 130b UP3 1.5
1.7
2.6 		< 0.0001
 = 0.0002
 0.0001 		28192399
GSE55323, GSE26245, GSE26247, GSE65061, GSE62610, GSE46738 Recurrent/non-recurrent Frozen and FFPE tissue 301b UP3 NA 0.0066 28651018
GSE36803 Tumor/normal Frozen tissue 130b UP2 < 1.5 0.0019 23233736
NA Tumor/normal FFPE tissue 130b UP2 2.2 0.02 27120795
NA Resistant/sensitive to docetaxel Cell lines 301b UP1 2.2 0.002 24714754
GSE14857 Tumor/normal Frozen tissue 130b UP1 1.5 0.0006 19676045
E-TABM-794 Tumor/normal Frozen tissue 130b and 301b UP1 > 1.5 < 0.05 21765474
NA PrCa patients/Normal control individuals
PrCa metastatic/PrCa localized patients 		Plasma 130b UP1 4.7
6.1 		0.034
0.007 		22240788
E-MTAB-408 Primary tumor/BPH Frozen tissue 130b UP1 2.00 0.00019 22266859
E-MTAB-408 CRPCs/BPH Frozen tissue 130b UP1 2.5 0.011 22266859
NA C4-2B/RWPE-1
C4-2B/RWPE1 derived exosomes 		Cell lines 130b UP1 ~ 2,
3.7 		< 0.05 24715691
GSE62610 Recurrent/non-recurrent FFPE tissue 301b UP1 2 0.025 25416653
NA Exosomes/cell line Cell lines 130b UP1 8.6 NA 27102850
NA Short/long overall survival FFPE tissue 301b UP1 NA 0.029 27307749
NA Hypoxia/normoxia Cell lline 301b UP1 > 2 NA 27327120
NA Patients/healthy donors Exosomes 130b UP1 NA 0.0021 28192399
NA Recurrent/non-recurrent Tissue 130b UP1 NA 0.018 28192399
NA After/before docetaxel Plasma and serum 301b UP1 1.6 0.04 24714754
GSE46738 High/Low pre-operatory PSA levels FFPE tissue 130b and 301b DOWN and UP1 − 1.3 and 1.2 < 0.049 and < 0.003 25663948
GSE55323 Recurrent/non-recurrent Tissue 301b DOWN4 − 1.2 0.017 24967583
NA Tumor/normal FFPE tissue 130b DOWN1 NA < 0.0001 25154741
NA Gleason 4 or 5/gleason 3
Recurrent/non-recurrent 		Serum 130b DOWN1 NA < 0.05 25874774
GSE52955 Tumor/normal Frozen tissue 130b and 301b DOWN1 NA < 0.0001 and 0.0014 28166834
  1. Disease condition and sample type are named according to the original study. References to the publications are presented as PMID. Data repository IDs: GSE corresponds to data deposited in Gene Expression Omnibus (GEO), and E-XXXX-XXX corresponds to data stored in Array Express. The fold change in expression between the conditions with its correlative p value were obtained from diverse sources which are indicated with superscript numbers in column “Change” as follows: 1. Identified and selected by the original publication, 2. Identified but not selected by the original publication, 3. Identified by analysis of the original study by others, 4. Identified in the present study by analysis of the original report
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Experimental Hematology & Oncology

ISSN: 2162-3619

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